Substrate Topography Modulates Cell Aging on a Progeria Cell Model
نویسندگان
چکیده
منابع مشابه
Progeria: a cell culture study on aging.
Progeria is an autosomal recessive disorder showing precocious senility. The cultured skin fibroblast from both the homozygous affected individual and the heterozygous parents can be distinguished from normals by decreased cell growth in culture. Mitotic activity, DNA synthesis, and cloning efficiency are markedly reduced.
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ژورنال
عنوان ژورنال: ACS Biomaterials Science & Engineering
سال: 2018
ISSN: 2373-9878,2373-9878
DOI: 10.1021/acsbiomaterials.8b00224